Influence of intraoperative episcleral application of topic mitomycin C on proliferation and differentiation of rabbit corneal and conjunctival epithelial cells

Autores: Marisa Braga Potério, Newton Kara-José, Eliane Maria Ingrid Amstalden, Keila Monteiro de Carvalho, Ana Maria Marcondes

Fonte: Revista Brasileira de Oftalmologia

Ano: 2014

DOI: 10.5935/0034-7280.20140034

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Resumo

Objective: To evaluate the influence of a three-minute application of 0.02% mitomycin C (MMC) on proliferation and differentiation of rabbit corneal epithelial cells. Methods: Topical MMC or 0.9% saline solution was applied to the episclera of the temporal limbal area of both eyes, maintaining intact epithelial tissue in one eye, and after partial corneal deepithelialization in the contralateral eye. The animals were arranged in groups A (20 eyes), B (16 eyes) and C (14 eyes) and sacrificed respectively on the […]

Tem experiência na área de Medicina, com ênfase em Cirurgia Oftalmológica, atuando na área acadêmica nas seguintes linhas de pesquisas: cirurgia estrabológica, ambliopia e visão binocular, baixa visão, qualidade de vida, auxílios ópticos, reabilitação visual e visão subnormal, educação médica, educação a distância.

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